Polymorphism of Drugs and the Problem of Creation of a New Generation of Pharmacological Agents
- The strategy of the search and development of new stereoselective drugs
- History of the development of the concept of polymorphism of chemical materials
- Stabilization of nonequilibrium conformers of an organic material in solutiondue to their association and subsequent solvation
- The investigation of the structure of polymorphous forms of 6-methyluracil by methods of quantum chemistry and molecular mechanics
- Physicochemical aspects of obtaining polymorphous modifications of drugs
- Granulometric composition and biononequivalence of barbital
- The investigation of diffusion properties of solutions of polymorphous modifications of 6-methyluracil
- Physicochemical properties of leocaine and features of its biological activity in a comparative aspect with dicain
- Pharmacodynamic characteristics of tetracaine and its metastable β-modification, leocaine, as agents of local anesthesia in ophthalmology
- A comparative study of leocaine and tetracaine as spinal anesthetics
- The effect of leocaine on excitability of the mycardium, exchange of ions, and membrane potentials of cardiomyocytes
- Structural features, physicochemical properties, and biological activity of betamecil on a comparative plane with methyluracil
- Features of molecular mechanisms of the biological activity of betamecil and methyluracil
- Betamecil as a stimulator of reparative regeneration of the cornea of the eye
- The effect of betamecil on the course of tuberculosis and sarcoidosis (experimental investigation)
- The effect of betamecil and methyluracil on dimensions of necrosis zones and reparative processes during an experimental infarct of the myocardium
- System of quick methods of integral evaluation of the biological activity of individual materials and complex preparations on biological objects
- Dry plant extracts – new technology, new quality
- Analysis and standardization of drugs, obtained by the method of polymorphous modification
- The problem of patent protection of individual polymorphous modifications of drugs
- The role of economic factors in the creation of new drugs